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REDEFINE 1 and REDEFINE 2 have enrolled approximately 4,600 adults with overweight or obesity

It was brutal

This is fundamentally different from taking melatonin

10.1016/j.freeradbiomed.2005.04.006

People with a lower starting body mass index tended to lose the highest percentage, while those carrying more weight lost a larger absolute number of pounds even if the percentage read lower