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The research question Koren and his team are now trying to answer: Can combining the two do more than either one alone

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Retatrutide at 12 mg produced ~67% GI events vs semaglutide 2.4 mg at ~74%

Avoid use in patients with a history of suicidal behavior, and discontinue therapy in patients who develop suicidal ideation

Choose injectable KPV when the target is outside the gut