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Some reversions, such as Arg242Tyr and Phe244Leu, substantially reduced activity on GD_M, whereas others, particularly in regions spanning residues 167 and 314439, maintained or improved activity (Supplementary Fig

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Long COVID, also known as post-acute sequelae of SARS-CoV-2 infection (PASC), is a chronic condition characterized by a range of persistent symptoms that last for weeks or months following the initial COVID-19 infection, affecting multiple organ systems and significantly impairing daily functioning and quality of life