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The physical combination of -arrestin2 and the IB-p65 complex stabilizes the spatial structure of IB, inhibits the inflammatory pathway NF-B, and proinflammatory cytokines such as interleukin 6 (IL-6), IL-8, and IL-1

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In summary, the injection of methylcellulose into the anterior chamber of the eye activates diverse cellular and molecular signals of stress at the level of RGCs, such as the upregulation of the GFAP and DNA damage

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