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[3] Sermorelin was originally approved in the 1990s for GH deficiency but was later discontinued as a commercial drug for business reasons (not due to safety or efficacy concerns)
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For comparison, semaglutide trials showed roughly 15% weight reduction over similar timeframes, and even tirzepatide topped out around 22% in its best-performing cohort
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References McCance RA, Sheldon W, Widdowson EM
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