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spending on prescription medication grew 11.4% in 2024 (up from 4.9% in 2023), a $50 billion increase, and GLP-1 medications accounted for 29% of this growth

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Composite outcome of CKD progression: defined as doubling of serum creatinine during follow up (mean serum creatinine during follow up divided by mean serum creatinine at index date 2) or incident stage 5 CKD during follow up period