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There is no linear dose-response relationship where more always equals better
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Food, beverages other than water, and other oral medications all interfere with SNAC's buffering capacity
A significant benefit in reducing death from cardiovascular causes was only shown in the LEADER trial with liraglutide (HR 0.78
Exercise stimulus should therefore be interpreted relative to substrate-supported regenerative capacity rather than caloric expenditure alone
Options include higher dosing to finish faster, freezing portions (accepting some potency loss), or accepting the waste as acceptable cost of the protocol
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