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They inhibit the enzyme DPP-4, thus impairing the rapid degradation of two key incretin hormones: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

Panda B, Chilvery S, Devi P, Kalmegh R, Godugu C

Collectively, our in vitro measurements suggest that the improvements in LaccID result from a combination of higher thermal stability and increased turnover at physiological pH (7 to 7.4) compared to LacAnc100

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These neuroprotective effects were linked to suppression of paraquat-induced activation of the MAPK signaling cascade, a pathway known to mediate oxidative and apoptotic damage in dopaminergic systems

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