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AngII has also been shown to enhance the expression of toll-like receptor 4 (TLR4), which in turn activates nuclear factor-kappa B (NF-B) in mesangial cells, amplifying the inflammatory response [19]

He W, Lam TK, Obici S, Rossetti L: Molecular disruption of hypothalamic nutrient sensing induces obesity

While there is no official "human dose" yet because it's still a research chemical, most lab studies use micro-doses to see these effects

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