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930 TRPM2 induces mitochondrial lipid peroxidation in hepatic I/R injury by increasing the expression of ALOX12, and TRPM2 inhibitors or calcium depletion significantly mitigate ferroptosis caused by hepatic IR injury both in vitro and in vivo
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By day 2 of the differentiation the cells should have transited through PS to DE, in accordance we observed a down-regulation of MIXL1, GSC, NODAL , and T levels, while markers of DE namely, FOXA2, SOX17, CER1, HHEX and GATA4 were significantly upregulated (see Fig
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