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Native rhIGF-1 (mecasermin, brand name Increlex) is FDA-approved only for the long-term treatment of growth failure in pediatric patients with severe primary IGF-1 deficiency or with GH gene deletion who have developed neutralizing antibodies to GH
If the power was out overnight (8+ hours), the interior temperature likely rose into the room temperature range, but it would have done so gradually, not all at once
Katout M, Zhu H, Rutsky J, Shah P, Brook RD, Zhong J, et al
doi: 10.1016/J.JAGP.2023.08.010 29 LiYPerryTKindyMSHarveyBKTweedieDHollowayHWet al
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