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Understanding the role of GLP-1 agonists in NAFLD management is increasingly relevant given the condition's high prevalence and limited pharmacological treatment options
Another phase III, randomized, open-label, non-inferiority, head-to-head trial, AWARD-6, evaluated dulaglutide (1.5 mg) versus liraglutide (1.8 mg) in patients with T2DM
Cells were treated with 5 or 10 mol/ml ASA (dissolved in 1 M Tris-HCl (pH 7.6) to a stock solution of 1 M and adjusted to pH 7.45 with 4 N HCl) for 48 hours
Moreover, taurine interferes with mitochondria-dependent apoptosis and the unfolded protein response [44], it downregulates the p53-Chk1 pathway [45] and upregulates extracellular-signal-regulated kinases (ERK) and Wnt/-catenin pathway [44, 46]
10.2337/diabetes.54.6.1615 7 ChuR
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