insulin glp-1 Genetics: How Genes Affect Appetite, Semaglutide, and Tirzepatide Response Frontiers | GLP-1 Receptor Agonists:

Pancreatitis : Both heavy alcohol use and GLP1 medications carry independent warnings for pancreatitis

Because Dihexa activates HGF/c-Met signaling , and this pathway is also involved in some types of tumor progression, caution is advised in: Patients with active cancers History of certain malignancies No human data confirms a cancer risk, but Dihexa is best avoided in patients with cancer unless under strict clinical supervision

Good news is that it's now been shown that after 1 year we can space out treatment (Q2W instead of QW) or replace it with oral one (more tolerated by patients) and keep (most of) the weight loss.

IFSO consensus on definitions and clinical practice guidelines for obesity management-an international Delphi study

J., & Castell, M

27 In a T2DM patient taking canagliflozin prior to a scheduled surgery, metabolic recovery did not occur until 6 days following the last dose of canagliflozin