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Glucagon-like peptide-1 receptor agonist treatment does not reduce abuse-related effects of opioid drugs
588,168 adults with type 2 diabetes: 139,546 started a GLP-1 drug 448,622 started an SGLT2 inhibitor Followed for up to 3 yearsAt 3 years, NAION was more frequent among people who started GLP-1 drugs: GLP-1 drugs: 39.1 cases per 10,000 persons SGLT2 inhibitors: 29.3 cases per 10,000 persons That works out to 6 to 10 extra cases per 10,000
Seven additional Phase 3 trials from the TRIUMPH program are expected to report results throughout 2026, including trials in type 2 diabetes, obstructive sleep apnea, and general obesity without specific comorbidities
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For the full picture on how glutathione fits into a skin health protocol alongside vitamin C, biotin, and collagen support, read the inside-out approach to glowing skin hub page
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