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[25] Rare but serious side effects include seizures, [10] [11] liver toxicity, [26] psychosis, [27] and risk of overdose
[7] [14] Many patients find that injection-related pain is generally mild, with the brief, pinching sensation most patients describe lasting only seconds
The studies showing meaningful weight loss with GLP-1 medications arent about raising GLP-1 levelstheyre about activating GLP-1 receptors at a different level than your body produces naturally
Less Common but Serious Side Effects Some less common but more serious GLP-1 side effects are worth being aware of: Pancreatitis (inflammation of the pancreas) Gallbladder problems (including gallstones) Acute kidney injury (usually as a result of severe dehydration from vomiting or diarrhea) Diabetic retinopathy worsening (particularly in patients with rapid improvement in blood sugar control) Hypoglycemia (when combined with other diabetes medications like sulfonylureas or insulin) All GLP-1 medications also carry a warning regarding a theoretical risk of medullary thyroid carcinoma, based on animal studies
Ramaekers V, Blau N
These medicines work best when theyre part of a complete plan, not just taken on their own.
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