BENZODIAZEPINE WITHDRAWAL SYMPTOMS PSYCHOLOGICAL SYMPTOMS Excitability (jumpiness, restlessness) Insomnia, nightmares, other sleep disturbances Increased anxiety, panic attacks Agoraphobia, social phobia Perceptual distortions Depersonalisation, derealisation Hallucinations, misperceptions Depression Obsessions Paranoid thoughts Rage, aggression, irritability Poor memory and concentration Intrusive memories Craving (rare) PHYSICAL SYMPTOMS Headache Pain/stiffness (limbs, back, neck, teeth, jaw) Tingling, numbness, altered sensation (limbs, face, trunk) Weakness (jelly-legs) Fatigue, influenza-like symptoms Muscle twitches, jerks, tics, electric shocks Tremor Dizziness, light-headedness, poor balance Blurred/double vision, sore or dry eyes Tinnitus Hypersensitivity (light, sound, touch, taste, smell) Gastrointestinal symptoms (nausea, vomiting, diarrhoea, constipation, pain, distension, difficulty swallowing) Appetite/weight change Dry mouth, metallic taste, unusual smell Flushing/sweating/palpitations Overbreathing Urinary difficulties/menstrual difficulties Skin rashes, itching Fits (rare) These symptoms have all been described by patients withdrawing from benzodiazepines

Ferroptosis: a trigger of proinflammatory state progression to immunogenicity in necroinflammatory disease
J Neurosci 20 : 89102
Possible side effects include: TRT Side Effects Elevated hematocrit (polycythemia) Acne or oily skin Fluid retention Testicular atrophy (manageable with hCG) Mood fluctuations during dose adjustments Potential fertility suppression Peptide Side Effects Injection site irritation or redness Temporary fluid retention Headaches or flushing Joint tightness (with GH-releasing peptides) Nausea (rare, more common with BPC-157) Sleep pattern adjustments Most side effects are dose-dependent and resolve with protocol adjustments
P., Schultz, G
A Phase II trial for corneal wound healing (NCT01452607) suggested efficacy in a specific ophthalmic application