Much remains to be examined, and studies will need to be performed in the coming years for definitive answers
Gastric Emptying Modulation : GLP-1 medications significantly reduce the rate at which food exits the stomach and enters the small intestine
A recent retrospective cohort also observed that, even in overweight patients without diabetes, the risk of primary open-angle glaucoma and ocular hypertension were significantly lower in the GLP-1RA group at both 3 and 5 years of follow-up (Vasu et al., 2025), suggesting the benefit of GLP-1RAs in the eye as an independent factor apart from blood glucose control
These diseases may include amyloidosis (a rare disease in which amyloid proteins build up in organs like the heart and kidneys), sarcoidosis (a disease that involves the growth of inflammatory cells in the body), or hemochromatosis (the buildup of too much iron in the body)
It stimulates the pancreas to release insulin when needed
Plus, it may also cause primary pulmonary hypertension or valvular heart disease, which is why people with existing or previous cardiovascular conditions should avoid it