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The liver plays a vital role in systemic metabolism by secreting hepatokines, which coordinate metabolic processes
Mei-Yeh, J., Deschenes, R
Adiponectin, an anti-inflammatory adipokine, typically rises
doi: 10.1155/2015/624627 35
While the use of amylin is efficient, patients have to inject it with each meal and in a separate injection from insulin
Importantly, delactylase enzymes, such as HDAC1, HDAC3, and SIRT family members, have been shown to remove lactyl groups in vitro, suggesting that non-histone lactylation is dynamically reversible and may constitute a regulatory network parallel to acetylation [94]
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