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Finally, delineating tissue-preferential effects is essential to determine whether improvements in IR arise primarily from reduced hepatic lipid content or also involve amelioration of pancreatic steatosis and skeletal muscle lipid metabolism

If nausea is severe or persistent beyond week 8, prescription ondansetron (Zofran) is a highly effective anti-nausea medication that blocks serotonin signals in the vomiting center

Randomization was stratified based on diagnosis of either FSAD, HSDD, or mixed

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Check for drug interactions - Some prescription medicines, like metformin, can deplete B12 over time

[PubMed] [JNeurosci] [PubMed] Fuentes-Albero M, Cauli O