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BMP-2 and BMP-7 FDA-approved for spinal fusion and fracture healing (recombinant protein formulations)
B12 absorption varies from person to person
Laboratory studies have highlighted possible roles in apoptosis regulation, insulin signaling, proteasome activity, and neurodegenerative disease models
Emmanuel Andrs, Thomas Vogel, Laure Federici, Jacques Zimmer, Ecaterina Ciobanu, and Georges Kaltenbach
Advanced / Aggressive Protocol (2 mL = ~10.0 mg/mL) Note: The 12 mg dose represents the highest dose tested in Phase 2 trials [3] [4] , producing maximum weight-loss efficacy (~24% body weight at 48 weeks)