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This binding triggers multiple physiological responses that contribute to glycemic control and weight reduction
Known adverse effect profile Gastrointestinal effects: Nausea represents the most common adverse effect, particularly during dose escalation
That year 390 million children and adolescents aged 5-19 were thought to be overweight, of whom 160 million were obese (WHO 2024)
Titration Complexities Slow titration, while necessary to reduce side effects, delays the onset of maximum efficacy
Lack of Improvement Over Time Side effects may sometimes stay the same or even worsen as treatment continues
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