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doi: 10.1016/j.neubiorev.2017.03.007 112 KrishnanV.NestlerE
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Flavonoids ameliorate ototoxic drug-induced hearing impairment by acting as ROS scavengers or inhibitors of JNK, MAPK, and other apoptotic signaling pathways, and by inhibiting aldose reductase activity, xanthine oxidase (Liao et al., 2024), common natural flavonoid mechanisms of action are described below
Link: Yoshino, J., et al
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The predicted molecular mass of the glutathione-epothilone conjugate was matched with those derived from SwissADME computational tools 814.03 m/z
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