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50 & Target In Vitro Increased efflux of Glutathione oxidized leads to glutathione depletion and may weaken the antioxidant defense of sickle erythrocytes [1]
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It is important to note that the apparent magnitude of the weight-loss effect is often influenced by baseline levels, control conditions, and follow-up windows
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The atherogenicity of Lp(a) is substantially greater than that of LDL on a per-particle basis, and elevated Lp(a) has been established as an independent risk factor for ASCVD, particularly in individuals with high LDL-C
Implication: The Regeneron/Hansoh deal was smaller than Metsera but signals another trend: companies are grabbing novel dual/triple agonizers wherever they arise
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