For retatrutide users, the bidirectional action of psyllium becomes particularly valuable
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It penetrates beneath the skin, breaking down the resilient fat cell walls and converting the fat into fatty acids
This particularly affects users with thicker skin or compromised barrier function that reduces penetration efficiency
When gut bacteria ferment fibre in the colon, they produce short-chain fatty acids (SCFAs) such as butyrate, propionate, and acetate, which directly stimulate GLP-1 release from intestinal L-cells
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