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TPP functions as a cofactor for several critical enzymes across three metabolic pathways: transketolase (TK) in the pentose phosphate pathway, pyruvate dehydrogenase (PDH) in glycolysis, and alpha-ketoglutarate dehydrogenase (AKD) in the Krebs cycle (6, 33, 34)

First, it stimulates insulin secretion from the pancreas when your blood sugar is high, helping to lower it effectively