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The eluted sample was quickly neutralized by addition of 1/10 volume of 1 M Tris pH 8.0 and further polished on a size-exclusion chromatography column (Superdex 75, GE healthcare) pre-equilibrated with phosphate-buffered saline (PBS, pH 7.4)
(PubMed) Marti-Carvajal AJ, Sola I, Lathyris D, Karakitsiou DE, Simancas-Racines D
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administered via single-dose autoinjector to abdomen or thigh Intranasal administration Studied extensively in Phase 2 trials but discontinued due to blood pressure elevations
Met is a potentially new therapeutic target for treatment of human melanoma
The triptan drugs (e.g., sumatriptan, rizatriptan, eletriptan, and almotriptan) act on several specific mechanisms of a migraine headache, such as promoting vasoconstriction and blocking pain pathways in the brainstem
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