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In evidence-based care, clinicians often slow titration or hold at an intermediate step when side effects kick up, GI comorbidities exist, or drug interactions complicate tolerability

At 10 years post-treatment, those who were treated with surgery lost an average of 21.6 percent of their body weight, compared to only 6.8 percent among those on medication

"A great jump start for weight loss," said Atlanta mom Ady Meshke, pictured above, about the GLP-1 meds that helped her lose 60 pounds

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Tirzepatide Brand names: Mounjaro (diabetes), Zepbound (weight management) Tirzepatide adds a second hormonal pathway to the GLP-1 mechanism: GIP (glucose-dependent insulinotropic polypeptide, a gut hormone that stimulates insulin release and influences how the body stores energy)