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This triple action creates additive effects that explain its impressive clinical trial results

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Dulaglutide is approved for T2DM management (Sanford, 2014), offering glycemic control and weight loss benefits comparable to liraglutide but with the added convenience of a weekly dosing regimen ( Semaglutide, another modified analog of human GLP-1, is resistant to DPP-4 degradation, which enables a once-weekly injection (Lau et al., 2015)

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Originally developed for Type 2 diabetes, it has proven effective for weight loss, leading to its approval for obesity management under the brand names Wegovy and Ozempic