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Other causes include scarring, sunlight, previous surgery, trauma, and facial palsy
Open Field On PND 27 and 28, two hours after the three-chamber test on PND 28, rats were subjected to the open field test to assess exploratory and locomotor activity (Deacon 2006)
doi:10.2165/00002512-200623100-00003
Regardless of the specific cause, multiple pathophysiological processes unfold simultaneously and in sequence, including endothelial dysfunction, alteration of the microcirculation, tubular injury, obstruction, venous congestion, and intrarenal inflammation