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1 This concern is especially relevant with the growing use of GLP-1 medications, which are effective for both diabetes glycemic control and obesity management

Some have struggled with high costs or limited insurance coverage, which can put treatment out of reach

Certain Crohn's presentations carry higher risk: stricturing disease (narrowed bowel segments), fistulas, or recent bowel resection may increase obstruction or perforation concerns with GLP-1-induced gastric stasis

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In the present study we sought to expand this concept by determining if shunting glutamate from the glutathione cycle can shape excitatory neurotransmission

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