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But its effects on the brain are increasingly well-documented and deserve serious attention in any discussion of neurological repair
& Grimm, S
By inhibiting NNMT, 5-Amino-1MQ increases nicotinamide pool availability (NAD+ precursors), elevates cellular SAM supporting methylation reactions, reduces adipogenesis, and enhances energy expenditure through improved mitochondrial function
Understanding the distinct mechanisms, potential interactions, and monitoring requirements is essential for informed clinical decision-making
Keith Lafferty MD, Fort Myers on October 10, 2025
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