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The reverse switch has its own considerations
This study could still be limited by the small sample size
Tirzepatide is not recommended during pregnancy or breastfeeding
1 6-8 2 2-3 Romrawin Clinic 3 1-2 4 5 6
Retatrutide, with triple-target effects (it works at the two receptors mentioned above and the glucagon receptor), caused people to lose about a quarter of their body weight after a year in a Phase II study (Jastreboff AM et al, N Engl J Med 2023;389(6):514526), although a follow-up study found the weight loss more in line with tirzepatide
The injection bypasses your digestive system entirely, so food in your stomach does not interfere with its absorption or mechanism of action
