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Oral Wegovys active ingredient is semaglutide, which is a type of large molecule called a peptide
only in early 2025 did the FDA announce the shortages were resolved (Feb 21, 2025)
Moreover, integration of continuous glucose monitoring (CGM) enables doses of GLP-1 to be titrated in real-time in response to GI patterns and closed-loop systems are under development, which may automatically regulate the delivery of medication
It is also worth noting that, consistent with other incretin-based and glucagon co-agonist therapies, small mean increases in heart rate were observed in the trial
But the finding that a significant number of women have fallen pregnant on these drugs and that a growing number of doctors are citing ovulation as a side effect has gobsmacked me
Antioxidants 12 (6), 1173
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