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L-citrulline avoids this fate, reaching the bloodstream intact
The caveat: cell culture upregulation doesn't automatically mean your blood cells are getting extended telomeres from a 10-day peptide course
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These outcomes highlight the intrinsic limitations of extrapolating from animal models, where dopamine circuitry and PDE10A distribution differ substantially from the chronically medicated, pathophysiologically altered human brain (Umbricht et al., 2021)
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