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415,416,417 GLP-1RAs can exert their local effects by activating vagal dendritic terminals that innervate the gut

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Annexin V binds phosphatidylserines that translocate to the outer leaflet of the membrane during early apoptosis 61 , whereas 7-AAD is a membrane-impermeable DNA dye that labels cells with compromised membrane integrity, identifying cells undergoing lytic forms of cell death such as necrosis, secondary necrosis and pyroptosis 62,63

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10.3390/pharmaceutics15010162 Pharmaceutics 90 RomaniniE.VolpatoA.Sifuentes dos SantosJ.de SantanaE