A second pathway, ERK1/2 signalling, governs cell survival and fibroblast activity, and appears especially relevant in tissue thats naturally poor in blood supply, tendons and ligament junctions being the clearest examples (Rodgers et al., 2025)
Gut microbiota-dependent trimethylamine N-oxide in acute coronary syndromes: a prognostic marker for incident cardiovascular events beyond traditional risk factors
Bottom Line: People on GLP-1s Should Be Monitored for Health Changes Experts say the findings should not discourage appropriate use of GLP-1 medications, which provide significant benefits for many people with diabetes and obesity, including improvements in heart health, kidney function, and liver disease
A GLP-1 Receptor Agonist Inhibits Aldosterone Release in Healthy Volunteers
PMID: 41838446 Kanumilli N et al
Its primary function is to regulate the levels of intracellular cysteine, which is essential for GSH synthesis