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While both methods aim to increase your B12 levels, they operate on very different timelines and through different biological pathways

Heres the most crucial thing to keep in mind: Within the first 48-72 hours, the B12 shots will lead to a rapid increase of immature red blood cells (reticulocytes)

There are two forms of B12methylcobalamin or cyanocobalamin

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What Works (Animal Studies) A 2025 systematic review presented at the American Academy of Orthopaedic Surgeons analyzed 39 studies from 1993-2024