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In this context, postbiotics are more plausibly positioned not as primary weight-loss interventions, but as nutritional strategies that may be continued after GLP-1based pharmacotherapy to support metabolic stability, mitigate weight regain, and preserve lean mass during the post-treatment phase ( From a clinical nutrition perspective, postbiotics should not be positioned as weight-loss agents, nor as substitutes for pharmacological GLP-1 receptor agonists

cDNA was amplified in MicroAmp Optical 96-well reaction plates with SYBR Green PCR Master Mix (Applied Biosystems) on an Applied Biosystems Prism 7000 sequence detection system

There is no trial that studied such a combination, which means anyone attempting it would be operating with zero efficacy evidence and stacked-up known risks

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adjusted pooled HR, 0.64

Our study showed a downregulation in Pparg expression after 16 weeks of HCHF intake