The three-point MACE risk reduction observed in SELECT suggests the potential for a new option in obesity treatment, addressing some of the leading causes of preventable death worldwide. Analyses of the three components in MACE showed that the risk of non-fatal myocardial infarction or heart attack was reduced by 28% compared to placebo (HR: 0.72
Even nutritious foods can cause discomfort when consumed in quantities that exceed the stomach's capacity
However, larger and longer-term studies are still needed to comprehensively evaluate its impact on key liver issues and fully assess its safety profile
The sustained benefit depends on continued medication use
As Blyumin put it, they were given limited use authorizations to compound these drugs that otherwise they shouldnt be able to, because theyre on patent. Now, those shortages have ended, and compounding pharmacies no longer have a legal basis for producing identical copies of GLP-1s
L., Amundsen, C., Balakrishnan, R., Binkley, G., Chan, E