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For example, in a 2021 study, as little as 100mg of dihydroberberine increased berberine blood levels better than 500mg of HCl, and another 2021 study (by Indena, the company that makes Berbevis) found that a phytosomal preparation resulted in a tenfold improvement in bioavailability compared with HCl.48 51 Based on these studies, you might conclude that the two bioenhanced forms are superior to berberine HCl
Copayments are expected to be high
Biomarkers we test for include CMP, Fasting Lipid, TSH with Reflex to T4, Hemoglobin A1C, and Insulin
Presented for research literature review only Mederacke I et al
Phytother Res PTR (2009) 23:1197204
The approval was granted based on demonstrated improvements in MASH and fibrosis, and a confirmatory study is currently underway
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