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The 12mg cohort achieved the highest mean body weight reduction at -24.2% exceeding all published results for semaglutide (approximately -16% in the STEP trials) and tirzepatide (approximately -22.5% in SURMOUNT-1) at their respective maximum doses

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A prior review cautioned that consumers who stop weight loss medication quickly regain the lost pounds, at a rate of 0.4 kg per month