"At Amgen, we believe that deep insights from observational research are critical to advancing patient care
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When semaglutide GLP-1 is injected into the body, it stimulates the pancreas, which in turn allows it to secrete insulin, and in turn, the insulin released helps lower a persons blood sugar level
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The peptide is stable in gastric acid, which makes oral administration viable for gut-targeted applications, a property that distinguishes it from many other therapeutic peptides that degrade before reaching target tissue
However, with the addition of each tag comes the risk that the native function of the protein may be abolished or compromised by interactions with the tag
