Similarly vitamin C, which is also naturally found in various food sources and is a major component of dietary vitamin supplements has recently been shown to kill drug-resistant Mycobacterium tuberculosis (Vilcheze et al., 2013), supporting the notion that antioxidants represent a promising novel strategy to remove the biofilms of pathogenic bacteria and prevent biofilm infections in clinical settings
For example, upregulation of HK2 expression promotes lactate production and induces dopaminergic neuron apoptosis
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