The semaglutide group had a 0.33 percentage point reduction in HbA1c ( P = .034), a 0.37 mmol/L decrease in total cholesterol ( P = .04) and a 0.29 mmol/L decline in LDL cholesterol ( P = .05) from baseline to 1 year
Frequently asked questions Are Wegovy and Ozempic the same thing
Stimulant laxatives (senna, bisacodyl): senna has better evidence in support of its use for (general) chronic constipation than bisacodyl, but neither has been specifically recommended for treating GLP-1 constipation
an Deinen Therapeuten
A controlled, dose-response study
However, if accompanied by severe abdominal pain, persistent vomiting, bloody stools, or significant weight loss beyond expected therapeutic effects, medical evaluation is warranted to rule out other gastrointestinal conditions