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2012;7:e49062
Upon binding to IGF-1R, the peptide initiates multiple intracellular signaling cascades, including the phosphoinositide 3-kinase (PI3K)/Akt/mTOR pathway, which regulates protein synthesis and cell growth, and the mitogen-activated protein kinase (MAPK) pathway, which controls cell proliferation and survival
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Organ margins that were once obscured become more distinct
however, the difference between the two groups was not significant
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