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In this paper, we aimed to summarize and discuss the potential extracerebral and cerebral mechanisms of stroke protection by GLP-1RAs, based on a review of both non-clinical and clinical studies that evaluated the mechanistic effects of GLP-1 and/or GLP-1RAs in preventing ischemic stroke
Common side effects include nausea, diarrhea, and vomiting
Losing weight reduces this load, alleviating pain associated with conditions like osteoarthritis
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A broader review of real-world evidence puts first-year discontinuation across studies in the range of 20% to 50%, with real-world weight outcomes generally falling below trial results, except among the most adherent patients, whose outcomes approach what trials reported
As a revolutionary cancer treatment, Keytruda (Pembrolizumab), first approved by the U.S
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