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The STEP 1 trial demonstrated a mean body weight reduction of 14.9% at the 2.4mg maintenance dose over 68 weeks, compared to just 2.4% in the placebo group

NICE guidance specifies a maximum treatment duration of two years in this setting

doi: 10.1016/j.cmet.2014.10.006 44 JamesonEQuareshyMChenY

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Influence gut-brain signaling For some patients, combining the two may increase the likelihood of: Nausea Bloating Digestive discomfort For others, cannabisparticularly CBDmay help manage nausea symptoms associated with GLP-1 medications

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