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This is the intended therapeutic effect, but it can feel unusual initially
We have virtually no large-scale human clinical trials to validate safety
However, when using semaglutide for weight loss, some people may experience a reduction in overall body weight, which can include a combination of fat and muscle loss
Long-term use of semaglutide in the presence of unmanaged acid reflux could potentially lead to complications associated with chronic GERD, such as esophagitis or Barretts esophagus
Ighodaro OM, Akinloye OA
The gut effects ride the GLP-1 arm, peak during titration, then ease
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