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Those are legitimate research directions, but they remain secondary endpoints and specific-population findings not a general cardiovascular-outcomes claim

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Meanwhile, the CRISPR-Cas9 gene editing system, originally derived from bacterial immune defense, has emerged as a powerful tool for correcting genetic disorders

Comparing with wild genotype (CC), the heterozygote (CT) and mutation homozygote (TT) lead to the decline of enzyme activity by about 34 and 75%, and increased thermolability in lymphocyte extracts 25

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doi: 10.1007/s11064-022-03743-5 65 LeiTYYeYZZhuXQSmerinDGuLJXiongXXet al