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Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells
Deep enough to reach upper papillary dermis where fibroblasts live
Reapply as needed, especially when exposed to sunlight
Vilsbll, T., Christensen, M., Junker, A
Mechanistically, we show that this effect occurs independently of canonical melatonin receptor signaling in ILC2s and instead requires activation of the NRF2-glutathione axis
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